Objective： To learn more about work stress， coping style and psychological health level of young medical staff in a Grade A tertiary hospital， explore related influencing factors， provide data support for improving the psychological health level of young medical staff， and put forward corresponding countermeasures and suggestions.,Methods,2,194 young medical staff in a Grade A tertiary hospital of traditional Chinese medicine were investigated by work stress scale， coping style scale and symptom checklist. Descriptive statistics， correlation analysis and multiple regression analysis were used to obtain the factors affecting psychological health level.,Results,2,the average score of work stress of all the young medical staff was （88.79±16.05）， and the dimensions with the highest score were workload and external environment. The average score of coping style was （88.79±16.05）， and the dimensions with the highest score were problem solving and help seeking. The average score of psychological health was （143.95±11.86）， mainly manifested as compulsion and interpersonal sensitivity. Workload， career development， interpersonal relationship in work stress and self-blame in coping style are positively correlated with psychological health level. Workload， career development， interpersonal relationship in work stress， self-blame and avoidance in coping style have significant positive predictive effect on SCL-90， while problem solving has significant negative predictive effect on SCL-90.,Conclusion,2,young medical staff are under great work pressure. Work stress can be relieved from workload， external environment and interpersonal relationship； young medical staff can be guided and trained to adopt mature coping styles to promote the psychological health of young medical staff.