Objective： To observe the clinical efficacy of Modified Sijunzi Decoction in treating perennial allergic rhinitis with syndrome of deficiency of lung and spleen qi.,Methods,2,One hundred and eighteen cases of perennial allergic rhinitis with syndrome of deficiency of lung and spleen qi were included as subjects， and were randomly divided into the treatment group and control group， 59 cases in each group. The treatment course was 4 weeks in both groups. The clinical efficacy， VAS score， quadrant score， nasal endoscopy score and TCM syndrome score were compared between the two groups.,Results,2,①During the treatment， 2 cases fell off in each group， and no adverse reactions were found in all cases. ②After treatment for 4 weeks， the total effective rates of the treatment group and the control group were 91.23% and 75.44% respectively， with statistically significant difference （,P,<,0.05）. ③The VAS score， quartile score， size of inferior nasal concha and nasal mucosa color score in the treatment group were lower than those in the control group. There were statistically significant differences between the two groups in the improvement of large amount of clear runny nose， shortness of breath， weakness， loose stool， cold prone， nasal congestion， runny nose symptoms and size of inferior nasal concha （,P,<,0.05）.,Conclusion,2,Compared with cetirizine hydrochloride alone， Modified Sijunzi Decoction combined with cetirizine hydrochloride shows better improvements on nasal congestion， runny nose， size of inferior nasal concha， large amount of runny nose， shortness of breath and fatigue， loose stool and cold prone.