非酒精性脂肪性肝病患者进食夜宵情况的横断面调查

王欣; 许怡; 安梓铭; 曾文丽; 辛鑫; 胡义扬; 冯琴; 王芳; 王唯坚

doi:10.16306/j.1008-861x.2022.S1.007

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非酒精性脂肪性肝病患者进食夜宵情况的横断面调查

临床研究 | 更新时间：2022-08-29

- 非酒精性脂肪性肝病患者进食夜宵情况的横断面调查
- A cross⁃sectional survey on midnight snack in patients with non⁃alcoholic fatty liver disease
- 上海中医药大学学报 2022年36卷第S1期页码：27-30
- 作者机构：
  
  1.上海中医药大学附属曙光医院肝病研究所（上海　201203）
  2.上海中医药大学附属曙光医院体检中心（上海　201203）
- 作者简介：
  
  王欣，男，在读硕士生，主要从事非酒精性脂肪性肝病的临床和基础研究
  王芳，主管护师；E-mail： sgyykfbwf@163.com
  王唯坚，主任医师；E-mail： wwjhxj@163.com
- 基金信息：
  
  上海市科委科技支撑计划项目(19401972100)
- DOI：10.16306/j.1008-861x.2022.S1.007
  中图分类号：
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王欣,许怡,安梓铭等.非酒精性脂肪性肝病患者进食夜宵情况的横断面调查[J].上海中医药大学学报,2022,36(S1):27-30.

WANG Xin,XU Yi,AN Ziming,et al.A cross⁃sectional survey on midnight snack in patients with non⁃alcoholic fatty liver disease[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(S1):27-30.
王欣,许怡,安梓铭等.非酒精性脂肪性肝病患者进食夜宵情况的横断面调查[J].上海中医药大学学报,2022,36(S1):27-30. DOI： 10.16306/j.1008-861x.2022.S1.007.

WANG Xin,XU Yi,AN Ziming,et al.A cross⁃sectional survey on midnight snack in patients with non⁃alcoholic fatty liver disease[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(S1):27-30. DOI： 10.16306/j.1008-861x.2022.S1.007.

摘要

目的,2,采用横断面调查方法，探讨非酒精性脂肪性肝病（NAFLD）患者进食夜宵情况。,方法,2,以上海中医药大学附属曙光医院体检人群为对象，抽样调查NAFLD组及非NAFLD组人群体重、BMI、血糖、血脂、肝功能、尿酸等机体代谢相关指标以及进食夜宵频率、进食量、进食种类情况。,结果,2,①NAFLD组人群体重、腰围、BMI显著高于非NAFLD组人群（,P,<,0.05）。②NAFLD组人群血清ALT、AST、γ-GT活性、FBG、LDL指标与非NAFLD组人群相比已出现升高趋势（,P,<,0.05）。③NAFLD组人群血清TG、TC、UA含量均显著高于非NAFLD组人群（,P,<,0.05）。④NAFLD组人群进食夜宵的比例显著高于非NAFLD组人群（,χ,²=10.058，,P,=0.002）。⑤与非NAFLD组人群比较，NAFLD组人群每周进食夜宵频次差异具有统计学意义（,χ,²=6.112，,P,=0.013）。⑥进食夜宵的种类，NAFLD组人群以海鲜烧烤类、甜点类、含糖饮料类为主，非NAFLD组人群则以水果蔬菜类、牛奶乳制品类、坚果类为主。,结论,2,NAFLD人群进食夜宵比例、每周进食夜宵次数均高于非NAFLD组人群，且两组人群进食夜宵种类不同；进食夜宵可能是导致NAFLD的重要危险因素。

Abstract

Objective： To investigate the midnight snack in patients with non-alcoholic fatty liver disease （NAFLD） based on cross-sectional survey.,Methods,2,Taking the physical examination population from Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine as the subjects， the body weight， BMI， blood glucose， blood lipid， liver function， uric acid and other related indexes of body metabolism， as well as the frequency， amount and type of midnight snack in NAFLD group and non-NAFLD group were investigated by sampling.,Results,2,①The body weight， waist circumference and BMI of NAFLD group were significantly higher than those of non-NAFLD group （,P,<,0.05）. ②Compared with non-NAFLD group， the serum levels of ALT， AST， γ-GT， FBG， and LDL in the NAFLD group showed increase tendency （,P,<,0.05）. ③The serum contents of TG， TC and UA in NAFLD group were significantly higher than those in non-NAFLD group （,P,<,0.05）. ④The proportion of people with midnight snack in NAFLD group was significantly higher than that in non-NAFLD group （,χ,²=10.058， ,P,=0.002）. ⑤There was statistically significant difference on the frequency of midnight snack every week between NAFLD group and non-NAFLD group （,χ,²=6.112， ,P,=0.013）. ⑥For the types of midnight snack， seafood barbecue， dessert and sugary drinks were often found in NAFLD group， while fruits and vegetables， milk， dairy products and nuts were observed in non-NAFLD group.,Conclusion,2,The proportion and the times per week of midnight snack in NAFLD group are higher than those in non-NAFLD group， and the type of midnight snack is different between the two groups. Midnight snack may be an important risk factor for NAFLD.

关键词

非酒精性脂肪性肝病进食夜宵横断面调查

Keywords

non-alcoholic fatty liver diseasemidnight snackcross-sectional survey

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