盆炎方联合针刺治疗气滞血瘀型盆腔炎性疾病后遗症的临床疗效

徐维娜; 陈双佳; 顾申枫; 陈逸嘉

doi:10.16306/j.1008-861x.2022.02.005

您当前的位置：

首页 >

文章列表页 >

盆炎方联合针刺治疗气滞血瘀型盆腔炎性疾病后遗症的临床疗效

临床研究 | 更新时间：2022-08-29

- 盆炎方联合针刺治疗气滞血瘀型盆腔炎性疾病后遗症的临床疗效
- Clinical effects of Penyan Formula combined with acupuncture on sequelae of pelvic inflammatory disease with qi stagnation and blood stasis type
- 上海中医药大学学报 2022年36卷第2期页码：26-30
- 作者机构：
  
  1.上海中医药大学（上海　201203）
  2.上海市浦东新区周家渡社区卫生服务中心（上海　200126）
  3.上海市浦锦社区卫生服务中心（上海　201112）
  4.上海市静安区中心医院（上海　200040）
  5.上海中医药大学附属龙华医院（上海　200032）
- 作者简介：
  
  徐维娜，女，在读硕士生，主治医师，主要从事中西医结合妇科临床研究
  陈逸嘉，主治医师；E-mail： 742886487@qq.com
- 基金信息：
  
  上海市闵行区科委自然基金资助项目(2020MHZ099);上海中医药大学附属龙华医院爱建捐赠基金项目(Y1713);上海中医药大学第20期课程建设项目(SHUTCM2021KC115)
- DOI：10.16306/j.1008-861x.2022.02.005
  中图分类号：
扫描看全文
徐维娜,陈双佳,顾申枫等.盆炎方联合针刺治疗气滞血瘀型盆腔炎性疾病后遗症的临床疗效[J].上海中医药大学学报,2022,36(02):26-30.

XU Weina,CHEN Shuangjia,GU Shenfeng,et al.Clinical effects of Penyan Formula combined with acupuncture on sequelae of pelvic inflammatory disease with qi stagnation and blood stasis type[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(02):26-30.
徐维娜,陈双佳,顾申枫等.盆炎方联合针刺治疗气滞血瘀型盆腔炎性疾病后遗症的临床疗效[J].上海中医药大学学报,2022,36(02):26-30. DOI： 10.16306/j.1008-861x.2022.02.005.

XU Weina,CHEN Shuangjia,GU Shenfeng,et al.Clinical effects of Penyan Formula combined with acupuncture on sequelae of pelvic inflammatory disease with qi stagnation and blood stasis type[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(02):26-30. DOI： 10.16306/j.1008-861x.2022.02.005.

摘要

目的,2,观察盆炎方联合针刺治疗气滞血瘀型盆腔炎性疾病后遗症（SPID）的临床疗效。,方法,2,纳入108例气滞血瘀型SPID患者，随机分为指南组、中药组、针药组，每组各36例。指南组患者给予膈下逐瘀汤口服，中药组患者给予盆炎方口服，针药组患者在中药组治疗基础上结合针刺治疗。治疗周期为3个月经周期。评价3组患者的临床疗效；治疗前后，采用视觉模拟评分法（VAS）评价患者的主观疼痛程度，检测患者的白介素-10（IL-10）和肿瘤坏死因子-α（TNF-α）水平。,结果,2,①治疗后，指南组、中药组、针药组的临床总有效率分别为61.11%、72.22%、86.11%，3组比较差异有统计学意义（,P,<,0.05），针药组的疗效优于中药组、指南组（,P,<,0.05），中药组的疗效优于指南组（,P,<,0.05）。②治疗后，3组患者的VAS评分均显著降低（,P,<,0.05），且针药组的评分低于中药组、指南组（,P,<,0.05），中药组的评分低于指南组（,P,<,0.05）。③治疗后，3组患者的血清TNF-α水平均降低、IL-10水平均升高（,P,<,0.05），且针药组患者的IL-10水平高于指南组、中药组（,P,<,0.05），中药组患者的IL-10水平高于指南组（,P,<,0.05），针药组患者的TNF-α水平低于指南组、中药组（,P,<,0.05）。,结论,2,盆炎方联合针刺治疗气滞血瘀型SPID，能有效改善患者的疼痛症状，调节相关炎性指标水平，值得临床推广。

Abstract

Objective： To observe the clinical effects of Penyan Formula combined with acupuncture on sequelae of pelvic inflammatory disease （SPID） with qi stagnation and blood stasis type.,Methods,2,A total of 108 SPID patients with qi stagnation and blood stasis type were included and randomly divided into the guideline group， traditional Chinese medicine group and acupuncture combined with traditional Chinese medicine group， 36 cases in each group. The patients in the guideline group were orally treated with Gexia Zhuyu Decoction， the patients in traditional Chinese medicine group were orally treated with Penyan Formula， and the patients in the acupuncture combined with traditional Chinese medicine group were treated with acupuncture based on the treatment of traditional Chinese medicine group. The treatment course was three menstrual cycles. The clinical effects of the three groups were evaluated. Before and after treatment， the subjective pain of the patients was evaluated by visual analogue scale （VAS）， and the levels of interleukin （IL）-10 and tumor necrosis factor-α （TNF-α） were detected.,Results,2,①After treatment， the clinical total effective rates of the guideline group， traditional Chinese medicine group and acupuncture combined with traditional Chinese medicine group were 61.11%， 72.22% and 86.11% respectively， with a statistical difference among the three groups （,P,<,0.05）. The effect of the acupuncture combined with traditional Chinese medicine group was better than that of traditional Chinese medicine group and the guideline group （,P,<,0.05）， and the effect of traditional Chinese medicine group was better than that of the guideline group （,P,<,0.05）. ②After treatment， the VAS scores of the three groups were significantly decreased （,P,<,0.05）， and the score of the acupuncture combined with traditional Chinese medicine group was lower than that of traditional Chinese medicine group and the guideline group （,P,<,0.05）， the score of traditional Chinese medicine group was lower than that of the guideline group （,P,<,0.05）. ③ After treatment， the levels of the serum TNF-α in the three groups were decreased and the levels of IL-10 were increased （,P,<,0.05）， and the level of IL-10 in the acupuncture combined with traditional Chinese medicine group was higher than that in the guideline group and traditional Chinese medicine group （,P,<,0.05）， the level of IL-10 in traditional Chinese medicine group was higher than that in the guideline group （,P,<,0.05）， the level of TNF-α in the acupuncture combined with traditional Chinese medicine group was lower than that in the guideline group and traditional Chinese medicine group （,P,<,0.05）.,Conclusion,2,Penyan Formula combined with acupuncture can effectively improve the pain symptom and regulate the levels of the related inflammatory indexes in the treatment of SPID with qi stagnation and blood stasis type， which is worth popularizing in clinic.

关键词

盆腔炎性疾病后遗症盆炎方针药结合白介素-10肿瘤坏死因子-α

Keywords

sequelae of pelvic inflammatory diseasePenyan Formulaacupuncture combined with medicineinterleukin-10tumor necrosis factor-α

references

丰有吉. 妇产科学［M］. 3版. 北京：人民卫生出版社， 2016： 267-272.

阮越容，董莉，胡国华. 朱氏盆炎汤治疗湿热瘀结型慢性盆腔炎临床研究［J］. 河南中医， 2017， 37（2）： 302-304.

李祥云工作室．李祥云治疗妇科病精华［M］. 北京：中国中医药出版社，2007： 638-639.

王玫君. 针刺结合盆浴治疗湿热型慢性盆腔炎临床研究［D］. 广州：广州中医药大学， 2020.

刘晓娟，范爱萍，薛凤霞. 《2015年美国疾病控制和预防中心关于盆腔炎性疾病的诊治规范》解读［J］. 国际妇产科学杂志，2015， 42（6）： 674-675，684.

曹泽毅. 中华妇产科学［M］. 2版. 北京：人民卫生出版社， 2006： 1466-1475.

中华中医药学会. ZYYXH/T203~246－2012中医妇科常见病诊疗指南［M］. 北京：中国中医药出版社，2012： 117-119.

罗颂平. 中医妇科学［M］. 北京：中国医药科技出版社，2002： 251-254.

郑筱萸. 中药新药临床研究指导原则（试行）［M］. 北京：中国医药科技出版社，2002： 243-253.

严广斌. 视觉模拟评分法［J］. 中华关节外科杂志（电子版），2014， 8（2）： 34.

梁学梅，金季玲. “四联疗法”治疗慢性盆腔炎临床经验［J］. 吉林中医药， 2011， 31（9）： 845-846.

牛颂歌. 康妇消炎栓联合桂枝茯苓胶囊治疗慢性盆腔炎83例疗效观察［J］. 长春中医药大学学报，2010， 26（4）： 564-565.

王慧敏. 慢性盆腔炎辨证规律研究研究［D］. 南京：南京中医药大学，2019.

金秀萍，马英兰. 血府逐瘀汤加减治疗慢性盆腔炎疗效及部分疗效机制研究［J］. 世界中医药，2020， 15（3）： 421-425.

利海波，李丽娟，林道莹. 血府逐瘀汤加减联合桂枝茯苓汤治疗气滞血瘀型慢性盆腔炎临床观察［J］. 四川中医，2018， 36（9）： 156-159.

隋凯悦. 血府逐瘀汤的妇科临床文献研究及导师陈莹教授运用该方的临证经验［D］. 沈阳：辽宁中医药大学，2016.

张双，高月平. 慢性盆腔炎的中西医研究进展［J］. 河南中医，2014， 34（3）： 497-499.

程航. 李祥云运用补肾祛瘀法治疗不孕症举隅［J］. 上海中医药杂志， 2005， 39（4）： 27-29.

程航，李祥云. 峻竣煎内服结合中药灌肠治疗输卵管阻塞性不孕102例［J］. 上海中医药大学学报， 2005， 19（2）： 22-23.

刘瑜，杜广中，卜彦青. 针灸治疗盆腔炎常用腧穴文献研究［J］. 上海针灸杂志， 2016， 35（2）： 227-229.

LIM S，KANG K W，PARK S Y， et al. Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by a novel compound， mercaptopyrazine， through suppression of nuclear factor-κB binding to DNA［J］. Biochem Pharmacol， 2004， 68（4）： 719-728．

浏览量

312

下载量

CSCD

CNKI被引量

文章被引用时，请邮件提醒。

提交

工具集

关联资源

抗炎通管汤对慢性输卵管炎模型大鼠IL-2、IL-6及TNF-α表达的影响