人参蛋白质组学研究进展
Research progress on proteomics of ginseng
- 上海中医药大学学报 2021年35卷第1期 页码：146-152
- 作者机构：
1.吉林大学生命科学学院（吉林 长春 130012）
- 作者简介：
李潇影，女，硕士，主要从事质谱相关的蛋白质组学基础研究
胡良海，教授，博士生导师；E-mail：lianghaihu@jlu.edu.cn
- 基金信息：国家自然科学基金资助项目(21675061)
DOI：10.16306/j.1008-861x.2021.01.019
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李潇影, 胡良海. 人参蛋白质组学研究进展[J]. 上海中医药大学学报, 2021,35(1):146-152.
LI Xiaoying, HU Lianghai. Research progress on proteomics of ginseng[J]. Academic Journal of Shanghai University of Traditional Chinese Medicine, 2021,35(1):146-152.
李潇影, 胡良海. 人参蛋白质组学研究进展[J]. 上海中医药大学学报, 2021,35(1):146-152. DOI： 10.16306/j.1008-861x.2021.01.019.
LI Xiaoying, HU Lianghai. Research progress on proteomics of ginseng[J]. Academic Journal of Shanghai University of Traditional Chinese Medicine, 2021,35(1):146-152. DOI： 10.16306/j.1008-861x.2021.01.019.
摘要
人参具有很高的药用价值和广泛的药理活性，蛋白质对于人参次级代谢产物的产生和营养价值的体现具有重要意义。运用蛋白质组学的思路和技术可绘制人参的蛋白质表达谱，以评价人参的药用活性与差异蛋白质之间的相关性，同时还可研究人参活性成分的生物合成途径等。通过总结国内外的相关文献，从样品制备、差异蛋白质组分析及功能蛋白质研究等方面对人参蛋白质组学的相关研究进展进行综述，为人参蛋白质组学的系统化研究提供参考。
Abstract
Ginseng shows high medicinal value and extensive pharmacological activities, and the proteins are of great importance for the production of secondary metabolites and the realization of nutritive value of ginseng.Proteomics ideas and techniques can be used to draw the protein expression profile of ginseng, evaluate the correlation between the medicinal activities and differential proteins of ginseng, as well as research the biosynthesis pathway of active constituents of ginseng.By summarizing the relevant domestic and foreign literatures, this paper reviews the relevant research advances of ginseng proteomics from the following aspects: sample preparation, differential proteome analysis, functional protein research and so on, in order to provide reference for the systematic study of ginseng proteomics.
关键词
人参蛋白质组学二维凝胶电泳质谱综述
Keywords
ginsengproteomicstwo-dimensional gel electrophoresismass spectrometryreview
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