Research progress of traditional Chinese medicine in treating diabetic kidney disease by regulating oxidative stress pathway

SU Yeyun; WANG Lili

doi:10.16306/j.1008-861x.2023.03.015

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Research progress of traditional Chinese medicine in treating diabetic kidney disease by regulating oxidative stress pathway

Review | 更新时间：2023-06-03

- Research progress of traditional Chinese medicine in treating diabetic kidney disease by regulating oxidative stress pathway
- Academic Journal of Shanghai University of Traditional Chinese Medicine Vol. 37, Issue 3, Pages: 92-101(2023)
- 作者机构：
  
  1.上海中医药大学附属曙光医院传统医学科（上海　201203）
- 作者简介：
- 基金信息：
- DOI：10.16306/j.1008-861x.2023.03.015
  CLC：
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苏叶昀,王丽莉.中医药通过调控氧化应激通路治疗糖尿病肾病研究进展[J].上海中医药大学学报,2023,37(03):92-101.

SU Yeyun,WANG Lili.Research progress of traditional Chinese medicine in treating diabetic kidney disease by regulating oxidative stress pathway[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2023,37(03):92-101.
苏叶昀,王丽莉.中医药通过调控氧化应激通路治疗糖尿病肾病研究进展[J].上海中医药大学学报,2023,37(03):92-101. DOI： 10.16306/j.1008-861x.2023.03.015.

SU Yeyun,WANG Lili.Research progress of traditional Chinese medicine in treating diabetic kidney disease by regulating oxidative stress pathway[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2023,37(03):92-101. DOI： 10.16306/j.1008-861x.2023.03.015.

摘要

糖尿病肾病（DKD）是糖尿病的重要并发症，其发病机制至今尚未完全明确。研究证实氧化应激对DKD病程进展意义重大，抑制氧化应激能有效延缓DKD病情发展、改善DKD预后。中医药具有多靶点、多通路的治疗特点，深入了解中医药对DKD氧化应激通路的调控作用，有助于探究中医药防治DKD的作用机制，为今后进一步开展更多高质量的循证研究提供理论依据。

Abstract

Diabetic kidney disease （DKD） is a major complication of diabetes， the pathogenesis of which has not yet been fully understood. Studies confirmed that oxidative stress is of great significance to the progression of DKD， and inhibiting oxidative stress can effectively delay the development of DKD and improve the prognosis of DKD. Traditional Chinese medicine （TCM） has the characteristics of multi-target and multi-pathway therapy. In-depth understanding of the regulatory effect of TCM on DKD oxidative stress pathway will be helpful to explore the mechanism of TCM in preventing and treating DKD， and provide a theoretical basis for further conducting more high-quality evidence-based research in the future.

关键词

糖尿病肾病氧化应激信号通路中医药综述

Keywords

diabetic nephropathyoxidative stresssignaling pathwaytraditional Chinese medicinereview

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