Clinical observation on efficacy of acupuncture combined with traditional Chinese medicine for treating polycystic ovary syndrome patients with kidney Yang deficiency syndrome

Bingyi YANG; Huanli SHI; Yichen ZHOU; Qitian LU; Xiuqi YIN

doi:10.16306/j.1008-861x.2022.S1.022

您当前的位置：

首页 >

文章列表页 >

Clinical observation on efficacy of acupuncture combined with traditional Chinese medicine for treating polycystic ovary syndrome patients with kidney Yang deficiency syndrome

Clinical Research | 更新时间：2022-08-29

- Clinical observation on efficacy of acupuncture combined with traditional Chinese medicine for treating polycystic ovary syndrome patients with kidney Yang deficiency syndrome
- Academic Journal of Shanghai University of Traditional Chinese Medicine Vol. 36, Issue S1, Pages: 88-92(2022)
- 作者机构：
  
  1.上海中医药大学附属曙光医院妇产科（上海　200021）
  2.洛阳市中医院妇科（河南　洛阳　471000）
- 作者简介：
- 基金信息：
- DOI：10.16306/j.1008-861x.2022.S1.022
  CLC：
扫描看全文
杨冰祎,石换利,周一辰等.针药结合治疗多囊卵巢综合征肾阳虚证患者的疗效观察[J].上海中医药大学学报,2022,36(S1):88-92.

YANG Bingyi,SHI Huanli,ZHOU Yichen,et al.Clinical observation on efficacy of acupuncture combined with traditional Chinese medicine for treating polycystic ovary syndrome patients with kidney Yang deficiency syndrome[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(S1):88-92.
杨冰祎,石换利,周一辰等.针药结合治疗多囊卵巢综合征肾阳虚证患者的疗效观察[J].上海中医药大学学报,2022,36(S1):88-92. DOI： 10.16306/j.1008-861x.2022.S1.022.

YANG Bingyi,SHI Huanli,ZHOU Yichen,et al.Clinical observation on efficacy of acupuncture combined with traditional Chinese medicine for treating polycystic ovary syndrome patients with kidney Yang deficiency syndrome[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(S1):88-92. DOI： 10.16306/j.1008-861x.2022.S1.022.

摘要

目的,2,观察针药结合治疗多囊卵巢综合征肾阳虚证患者的临床疗效。,方法,2,将92例多囊卵巢综合征肾阳虚证患者随机分为治疗组和对照组，每组46例。两组均予中药口服，治疗组加予针刺，对照组加予安慰针刺。两组疗程均为3个月经周期，观察中医证候疗效及安全性，比较月经周期、抗苗勒管激素（AMH）、促黄体生成素（LH）、卵泡刺激素（FSH）、睾酮（T）水平及排卵率情况。,结果,2,①治疗前，两组患者月经周期比较，差异无统计学意义（,P,>,0.05）。治疗后，两组的月经周期均明显缩短（,P,<,0.05），且治疗组对月经周期的改善优于对照组（,P,<,0.05）。②治疗组、对照组的中医证候疗效总有效率分别为91.30%、76.09%；组间中医证候疗效比较差异有统计学意义，治疗组疗效优于对照组（,P,<,0.05）。③治疗前后组内比较，治疗组FSH、LH、T水平差异有统计学意义，对照组LH、T水平差异有统计学意义（,P,<,0.05）；组间治疗后比较，治疗组LH水平明显低于对照组。④治疗组、对照组的排卵率分别为67.39%、36.96%，治疗组的排卵率明显高于对照组（,P,<,0.05）。⑤试验期间，两组均未出现不良反应事件。,结论,2,针药结合治疗肾阳虚型多囊卵巢综合征疗效较佳，能有效地改善多囊卵巢综合征肾阳虚证患者的中医证候和月经周期，调节性激素水平，提高排卵率。

Abstract

Objective,2,To observe the clinical effect of acupuncture combined with traditional Chinese medicine （TCM） on polycystic ovary syndrome patients with kidney Yang deficiency syndrome.,Methods,2,Ninety-two polycystic ovary syndrome patients with kidney Yang deficiency syndrome were randomly divided into treatment group and control group， 46 cases in each group. All patients were given TCM orally， acupuncture was added in the treatment group， and the placebo acupuncture was added to the treatment group in the control group. The treatment course of both groups was 3 menstrual cycles. The curative effect and safety of TCM syndrome were observed， and the menstrual cycle， anti-Mullerian hormone （AMH）， luteinizing hormone （LH）， follicle stimulating hormone （FSH）， testosterone （T） levels and ovulation rate were compared.,Results,2,①Before treatment， there was no statistical significance in menstrual cycle between two groups （,P,>,0.05）. After treatment， the menstrual cycle was significantly shortened in both groups （,P,<,0.05）， and the improvement in the treatment group was better than that in the control group （,P,<,0.05）. ②The total effective rate of TCM syndrome in treatment group and control group were 91.30% and 76.09%， respectively. There was statistically significant difference in TCM syndrome curative effect between two groups， and the curative effect of the treatment group was better than the control group （,P,<,0.05）. ③In intra-group comparison before and after treatment， there were statistically significant differences in FSH， LH and T levels in the treatment group， while there were statistically significant differences in LH and T levels in the control group （,P,<,0.05）. After treatment， the level of LH in the treatment group was significantly lower than that in the control group. ④The ovulation rates of treatment group and control group were 67.39% and 36.96% respectively， ovulation rate in treatment group was significantly higher than that in control group （,P,<,0.05）. ⑤During the experiment， there were no adverse event in the two groups.,Conclusion,2,The clinical effect of acupuncture combined with TCM on polycystic ovary syndrome patients with kidney Yang deficiency syndrome. The combination of acupuncture and TCM in the treatment of polycystic ovary syndrome patients with kidney Yang deficiency syndrome has a significant effect， which can effectively improve the TCM syndrome and menstrual cycle， regulate the level of sex hormones， improve ovulation rate．

关键词

针刺中药针药结合多囊卵巢综合征肾阳虚证临床研究

Keywords

acupuncturecombination of acupuncture and medicinepolycystic ovary syndromekidney Yang deficiency syndromeclinical observation

references

DE LEO V，MUSACCHIO M C，CAPPELLI V， et al. Genetic， hormonal and metabolic aspects of PCOS： an update［J］. Reprod Biol Endocrinol， 2016， 14： 38.

谢幸，苟文丽.妇产科学［M］.北京：人民卫生出版社，2013：359.

肖承悰.中医药治疗多囊卵巢综合征研究近况［J］.北京中医药大学学报，2007， 14（1）： 42-45.

李丹，谢敏，王中鹏.针灸治疗多囊卵巢综合征的优势与前景［J］.西部中医药，2019， 32（5）： 26-29.

陈鹏典，杨卓欣，刘芳，等.针药结合治疗多囊卵巢综合征促排卵的临床研究进展［J］.现代中西医结合杂志，2018， 27（35）： 3987-3990.

席瑾，陈昊，程洁，等. 针灸治疗多囊卵巢综合征的系统评价的质量评价［J］. 中国循证医学杂志， 2019， 19（2）： 83-89.

WU Y， ROBINSON N， HARDIMAN P J， et al. Acupuncture for treating polycystic ovary syndrome： guidance for future randomized controlled trials［J］. J Zhejiang Univ Sci B，2016， 17（3）：169-180.

Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome（PCOS）［J］.Hum Reprod， 2004， 19（1）： 41-47.

罗颂平.中医妇科学［M］.北京：高等教育出版社，2014：266.

国家药品监督管理局. 中药新药临床研究指导原则（试行）［M］. 北京：中国医药科技出版社，2002： 168.

冯光荣. 紫石英治疗不孕症源流考［J］. 中医临床研究， 2016， 8（28）： 147-148.

张伟，陈素红，吕圭源.菟丝子功效性味归经与现代药理学的相关性研究［J］. 时珍国医国药，2010， 21（4）： 808-811.

陈婷婷，傅萍，邢佳，等. 多囊卵巢综合征发病机制的影响因子研究［J］. 中国优生与遗传杂志， 2016， 35（11）： 122-125.

DEWAILLY D，PIGNY P，SOUDAN B，et al．Reconciling the definitions of polycystic ovary syndrome： the ovarian follicle numberand serum anti-Müllerian hormone concentrations aggregate withthe markers of hyperandrogenism［J］．J Clin Endocrinol Metab，2010，95（ 9）： 4399-4405．

PALOMBA S，FALBO A，ZULLO F．Management strategies for ovulation induction in women with polycystic ovary syndrome and known clomifene citrate resistance［J］ .Curr Opin Obstet Gynecol， 2009， 21： 465-473.

刘佳琪，王必勤.“调任通督针刺法”联合通元针法治疗多囊卵巢综合征不孕的疗效及对FSH、LH、E2和T水平影响［J］.针灸临床杂志，2020， 36（4）： 15-18.

许淑琴，李亚菊.温针灸“子宫穴”治疗女性不孕症48例［J］.针灸临床杂志，1999， 15（3）： 51-52.

王兴桂，付强.电针不同穴位对排卵障碍大鼠阴道细胞学检查及雌二醇水平的影响［J］.上海针灸杂志，2003， 22（7）： 35-36.

宋书昌，卢智.足三里穴证治机理探讨［J］.中医临床研究，2013， 5（22）： 38-40.

何婉珊. 穴位刺激配合辅助生殖技术提高妊娠结局的Meta分析及用穴规律研究［D］.广州：广州中医药大学， 2016.

Views

155

下载量

CSCD

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

Clinical efficacy evaluation of acupuncture in treating negative symptoms of schizophrenia

Research on effects and relevant mechanism of acupuncture on inflammation and respiratory function in animal models of asthma

A randomized controlled study of acupuncture in improving endometrial peristalsis and pregnancy outcomes at peri⁃transfer period in patients of in vitro fertilization⁃embryo transfer undergoing frozen embryo transfer

Clinical efficacy of traditional Chinese medicine combined with acupuncture on chronic heart failure （cardiac function grade Ⅱ） with Qi deficiency and blood stasis syndrome

Discussion on the effect mechanisms of acupuncture combined with Xishao Decoction in the treatment of pain from the theory of yin-yang coordination

Related Author

No data

Related Institution

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine

Shanghai Mental Health Center， Shanghai Jiao Tong University School of Medicine

Shanghai Baoshan District Mental Health Center

Shanghai Research Institute of Acupuncture and Meridian

Shanghai University of Traditional Chinese Medicine

⁰