Control study of tissue adhesive sandwich injection in treatment of Dieulafoy’s disease bleeding

Likun GUO; Rong CEN; Biao GONG; Shanying YANG; Jiajun ZHANG; Yuli WANG

doi:10.16306/j.1008-861x.2022.S1.018

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Control study of tissue adhesive sandwich injection in treatment of Dieulafoy’s disease bleeding

Clinical Research | 更新时间：2022-08-29

- Control study of tissue adhesive sandwich injection in treatment of Dieulafoy’s disease bleeding
- Academic Journal of Shanghai University of Traditional Chinese Medicine Vol. 36, Issue S1, Pages: 72-75(2022)
- 作者机构：
  
  1.上海中医药大学附属曙光医院内镜中心（上海　201203）
- 作者简介：
- 基金信息：
- DOI：10.16306/j.1008-861x.2022.S1.018
  CLC：
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郭丽坤,岑戎,龚彪等.应用组织粘合剂三明治注射法治疗Dieulafoy病出血的对照研究[J].上海中医药大学学报,2022,36(S1):72-75.

GUO Likun,CEN Rong,GONG Biao,et al.Control study of tissue adhesive sandwich injection in treatment of Dieulafoy’s disease bleeding[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(S1):72-75.
郭丽坤,岑戎,龚彪等.应用组织粘合剂三明治注射法治疗Dieulafoy病出血的对照研究[J].上海中医药大学学报,2022,36(S1):72-75. DOI： 10.16306/j.1008-861x.2022.S1.018.

GUO Likun,CEN Rong,GONG Biao,et al.Control study of tissue adhesive sandwich injection in treatment of Dieulafoy’s disease bleeding[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(S1):72-75. DOI： 10.16306/j.1008-861x.2022.S1.018.

摘要

目的,2,评价内镜下应用组织粘合剂三明治注射法治疗Dieulafoy病出血的治疗效果。,方法,2,将61例Dieulafoy病大出血患者随机分为A组和B组，A组31例、B组27例。A组予内镜下组织粘合剂三明治注射法止血，B组予内镜下高频电凝止血钳法止血。治疗后比较两组止血成功率、术后72 h内再出血率，同时观察术后有无异位栓塞、组织坏死等并发症。,结果,2,两组止血率无统计学差异（,P,>,0.05），但B组72 h再出血率明显高于A组，差异有统计学意义（,P,<,0.05）。,结论,2,组织粘合剂三明治注射法是Dieulafoy病胃镜止血的快速、有效、安全的治疗手段。

Abstract

Objective： To evaluate the treatment effect of endoscopic application of tissue adhesive sandwich injection in treatment of Dieulafoy’s disease bleeding.,Methods,2,A total of 61 patients with massive bleeding due to Dieulafoy’s disease were randomly divided into group A and group B， with 31 cases in group A and 27 cases in group B. Group A was given endoscopic cyanoacrylate sandwich injection for hemostasis， and group B was given endoscopic high-frequency electrocoagulation hemostatic forceps for hemostasis. After treatment， the success rate of hemostasis and the rate of rebleeding within 72 hours after operation were compared between the two groups. At the same time，the postoperative complications such as ectopic embolism and tissue necrosis were observed.,Results,2,There was no statistical difference in the hemostatic rate between the two groups（,P,>,0.05），but the 72-hour rebleeding rate in group B was significantly higher than that in group A， and the difference was statistically significant （,P,<,0.05）.,Conclusions,2,Tissue adhesive sandwich injection is a fast， effective and safe treatment for gastroscopic hemostasis in Dieulafoy’s disease.

关键词

Dieulafoy病急诊止血组织粘合剂临床观察

Keywords

Dieulafoy diseaseemergency treatmenthemostasistissue adhesiveclinical observation

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Related Institution

Department of Tradtional Chinese Medicine， Children’s Hospital Affilicated to Shanghai Jiao Tong University School of Medcine

Department of Emergency Internal Medicine， Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

Department of Nephropathy， Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

Shanghai Pudong New Area Guangming Hospital of Traditional Chinese Medicine

Department of Orthopedics and Traumatology, Affiliated Hospital of Chengde Medical College

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