A cross⁃sectional survey on midnight snack in patients with non⁃alcoholic fatty liver disease

Xin WANG; Yi XU; Ziming AN; Wenli ZENG; Xin XIN; Yiyang HU; Qin FENG; Fang WANG; Weijian WANG

doi:10.16306/j.1008-861x.2022.S1.007

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A cross⁃sectional survey on midnight snack in patients with non⁃alcoholic fatty liver disease

Clinical Research | 更新时间：2022-08-29

- A cross⁃sectional survey on midnight snack in patients with non⁃alcoholic fatty liver disease
- Academic Journal of Shanghai University of Traditional Chinese Medicine Vol. 36, Issue S1, Pages: 27-30(2022)
- 作者机构：
  
  1.上海中医药大学附属曙光医院肝病研究所（上海　201203）
  2.上海中医药大学附属曙光医院体检中心（上海　201203）
- 作者简介：
- 基金信息：
- DOI：10.16306/j.1008-861x.2022.S1.007
  CLC：
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王欣,许怡,安梓铭等.非酒精性脂肪性肝病患者进食夜宵情况的横断面调查[J].上海中医药大学学报,2022,36(S1):27-30.

WANG Xin,XU Yi,AN Ziming,et al.A cross⁃sectional survey on midnight snack in patients with non⁃alcoholic fatty liver disease[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(S1):27-30.
王欣,许怡,安梓铭等.非酒精性脂肪性肝病患者进食夜宵情况的横断面调查[J].上海中医药大学学报,2022,36(S1):27-30. DOI： 10.16306/j.1008-861x.2022.S1.007.

WANG Xin,XU Yi,AN Ziming,et al.A cross⁃sectional survey on midnight snack in patients with non⁃alcoholic fatty liver disease[J].Academic Journal of Shanghai University of Traditional Chinese Medicine,2022,36(S1):27-30. DOI： 10.16306/j.1008-861x.2022.S1.007.

摘要

目的,2,采用横断面调查方法，探讨非酒精性脂肪性肝病（NAFLD）患者进食夜宵情况。,方法,2,以上海中医药大学附属曙光医院体检人群为对象，抽样调查NAFLD组及非NAFLD组人群体重、BMI、血糖、血脂、肝功能、尿酸等机体代谢相关指标以及进食夜宵频率、进食量、进食种类情况。,结果,2,①NAFLD组人群体重、腰围、BMI显著高于非NAFLD组人群（,P,<,0.05）。②NAFLD组人群血清ALT、AST、γ-GT活性、FBG、LDL指标与非NAFLD组人群相比已出现升高趋势（,P,<,0.05）。③NAFLD组人群血清TG、TC、UA含量均显著高于非NAFLD组人群（,P,<,0.05）。④NAFLD组人群进食夜宵的比例显著高于非NAFLD组人群（,χ,²=10.058，,P,=0.002）。⑤与非NAFLD组人群比较，NAFLD组人群每周进食夜宵频次差异具有统计学意义（,χ,²=6.112，,P,=0.013）。⑥进食夜宵的种类，NAFLD组人群以海鲜烧烤类、甜点类、含糖饮料类为主，非NAFLD组人群则以水果蔬菜类、牛奶乳制品类、坚果类为主。,结论,2,NAFLD人群进食夜宵比例、每周进食夜宵次数均高于非NAFLD组人群，且两组人群进食夜宵种类不同；进食夜宵可能是导致NAFLD的重要危险因素。

Abstract

Objective： To investigate the midnight snack in patients with non-alcoholic fatty liver disease （NAFLD） based on cross-sectional survey.,Methods,2,Taking the physical examination population from Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine as the subjects， the body weight， BMI， blood glucose， blood lipid， liver function， uric acid and other related indexes of body metabolism， as well as the frequency， amount and type of midnight snack in NAFLD group and non-NAFLD group were investigated by sampling.,Results,2,①The body weight， waist circumference and BMI of NAFLD group were significantly higher than those of non-NAFLD group （,P,<,0.05）. ②Compared with non-NAFLD group， the serum levels of ALT， AST， γ-GT， FBG， and LDL in the NAFLD group showed increase tendency （,P,<,0.05）. ③The serum contents of TG， TC and UA in NAFLD group were significantly higher than those in non-NAFLD group （,P,<,0.05）. ④The proportion of people with midnight snack in NAFLD group was significantly higher than that in non-NAFLD group （,χ,²=10.058， ,P,=0.002）. ⑤There was statistically significant difference on the frequency of midnight snack every week between NAFLD group and non-NAFLD group （,χ,²=6.112， ,P,=0.013）. ⑥For the types of midnight snack， seafood barbecue， dessert and sugary drinks were often found in NAFLD group， while fruits and vegetables， milk， dairy products and nuts were observed in non-NAFLD group.,Conclusion,2,The proportion and the times per week of midnight snack in NAFLD group are higher than those in non-NAFLD group， and the type of midnight snack is different between the two groups. Midnight snack may be an important risk factor for NAFLD.

关键词

非酒精性脂肪性肝病进食夜宵横断面调查

Keywords

non-alcoholic fatty liver diseasemidnight snackcross-sectional survey

references

FARRELL G C， LARTER C Z. Nonalcoholic fatty liver disease： from steatosis to cirrhosis［J］. Hepatology， 2006， 43（2 Suppl 1）： S99-S112.

ZHOU J， ZHOU F， WANG W， et al. Epidemiological feature of NAFLD from 1999 to 2018 in China［J］. Hepatology， 2020， 71（5）：1851-1864.

ZHOU F， ZHOU J， WANG W， et al. Unexpected Rapid Increase in the Burden of NAFLD in China From 2008 to 2018： A Systematic Review and Meta-Analysis［J］. Hepatology， 2019， 70（4）： 1119-1133.

BARRERA F， GEORG J. The role of diet and nutritional intervention for the management of patients with NAFLD［J］. Clin Liver Dis， 2014， 18（1）： 91-112.

中华医学会肝病学分会脂肪肝和酒精性肝病学组，中国医师协会脂肪性肝病专家委员会. 非酒精性脂肪性肝病防治指南（2018年更新版）［J］. 临床肝胆病杂志，2018， 34（5）： 947-957.

HUNOT C， FILDES A， CROKER H， et al. Appetitive traits and relationships with BMI in adults： Development of the Adult Eating Behaviour Questionnaire［J］. Appetite， 2016， 105： 356-363.

魏晟，聂绍发，朱桂宝，等. 成年人饮食行为评价量表的信度、效度分析［J］. 医学与社会，2006， 19（7）： 20-23.

HOWELL M J， SCHENCK C H， CROW S J. A review of nighttime eating disorders［J］. Sleep Med Rev， 2009， 131（1）： 23-34.

樊蕊，王贝宁，苗泽宇，等. 北京某医学院校大学生食用宵夜情况调查［J］. 中国健康教育，2017， 33（9）： 845-847.

KINSEY A W， ORMSBEE M J. The health impact of nighttime eating： old and new perspectives［J］. Nutrients， 2015， 7（4）： 2648-2662.

KINSEY A W， EDDY W R， MADZIMA T A， et al. Influence of night-time protein and carbohydrate intake on appetite and cardiometabolic risk in sedentary overweight and obese women［J］. Br J Nutr， 2014， 112（3）： 320-327.

European Association for the Study of the Liver （EASL）， European Association for the Study of Diabetes （EASD）， European Association for the Study of Obesity （EASO）. EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease［J］. J Hepatol， 2016， 64（6）： 1388-1402.

KIM Y， CHANG Y， CHO Y K， et al. Metabolically healthy versus unhealthy obesity and risk of fibrosis progression in non-alcoholic fatty liver disease［J］. Liver Int， 2019， 39（10）： 1884-1894.

HIBI M， MASUMOTO A， NAITO Y， et al. Nighttime snacking reduces whole body fat oxidation and increases LDL cholesterol in healthy young women［J］. Am J Physiol Regul Integr Comp Physiol， 2013， 304（2）： R94-R101.

范建高. 加强非酒精性脂肪性肝病患者生活方式的管理［J］. 中华健康管理学杂志，2020， 14（4）： 308-312.

BERTHOUD H R， MORRISON C D， ACKROFF K， et al. Learning of food preferences： mechanisms and implications for obesity & metabolic diseases［J］. Int J Obes （Lond）， 2021， 45（10）： 2156-2168.

施军平，范建高. 脂肪性肝病诊疗规范化的专家建议（2019年修订版）［J］. 实用肝脏病杂志，2019， 22（6）： 787-792.

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Department of Emergency， Shuguang Hospital Affiliate to Shanghai University of Traditional Chinese Medicine

Department of Hepatology， Shuguang Hospital Affiliate to Shanghai University of Traditional Chinese Medicine

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine， Institute of Liver Diseases， Shanghai University of Traditional Chinese Medicine， Shanghai Key Laboratory of Traditional Chinese Clinical Medicine， Key Laboratory of Liver and Kidney Diseases， Ministry of Education

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