Objective： To observe the therapeutic effect and health economics evaluation of patients with acute cerebral infarction under the intervention mode of management pattern of stroke unit with integrated traditional Chinese and western medicine.,Methods,2,Ninety patients with acute cerebral infarction were randomly divided into treatment group and control group， 45 cases in each group. The treatment group was given the combined Chinese and western medicine stroke unit management model for intervention， and the control group was given the western medicine stroke unit management model. The treatment course of both groups was 2 weeks， followed up for 6 months. NIHSS score， Barthel index and related medical expenses were observed and compared.,Results,2,①There were statistically significant differences in NIHSS score and Barthel index between the two groups before treatment， 2 weeks after treatment and 6 months after treatment （,P,<,0.05）. The improvement of NIHSS score and Barthel index in the treatment group was better than that in the control group at 2 weeks and 6 months after treatment. The improvement of NIHSS score and Barthel index in the treatment group was better than that in the control group at 2 weeks and 6 months after treatment （,P,<,0.05）. ②The hospitalization cost in the treatment group was higher than that in the control group （,P,<,0.05）， but the total medical cost within 6 months in the treatment group was lower than that in the control group （,P,<,0.05）.,Conclusion,2,The management pattern of stroke unit with integrated traditional Chinese and western medicine can significantly improve the neurological deficit and daily living ability of patients with acute cerebral infarction， and reduce related medical expenses. It has good clinical efficacy and economic benefit.