Objective： To observe the clinical efficacy of acupoint catgut embedding in the prevention and treatment of postoperative pain of mixed hemorrhoids.,Methods,2,A total of 96 patients with mixed hemorrhoids were included and randomly divided into the treatment group A （single acupoint group）， treatment group B （multiple acupoint group） and control group， 32 cases in each group. All patients were treated with Milligan-Morgan hemorrhoidectomy and postoperative routine analgesia. Based on above treatment， the patients in the treatment group A were treated with catgut embedding at acupoint Changqiang （DU1） before operation， and the patients in the treatment group B were treated with catgut embedding at acupoints Changqiang （DU1） and Baihuanshu （BL30） before operation. On the 1st， 3rd， 5th， 7th and 14th days after operation， the visual analogue scale （VAS） was used to evaluate the usual pain， dressing change pain and defecation pain scores， and the scores of postoperative edema and bleeding symptoms of the three groups were compared. On the postoperative day， the urinary retention scores of the three groups were evaluated and compared. The use rate of analgesic drugs of the three groups was compared. On the 14th day after operation， the analgesic effects of the three groups were evaluated and compared.,Results,2,①On the 3rd， 5th， 7th and 14th days after operation， the scores of usual pain， dressing change pain and defecation pain in the treatment groups A and B were significantly lower than those in the control group （,P,<,0.01， ,P,<,0.05）， but there was no statistical difference in the pain scores between the two treatment groups （,P,>,0.05）. ②On the 5th day after operation， the scores of bleeding and edema in the treatment groups A and B were lower than those in the control group （,P,<,0.05）. On the 7th day after operation， the edema scores in the treatment groups A and B were also lower than those in the control group （,P,<,0.05）. On the postoperative day， there was no statistical difference in the urinary retention scores among the three groups （,P,>,0.05）. ③The use rate of analgesic drugs in the treatment groups A and B was significantly lower than that in the control group （,P,<,0.05）. There was no statistical difference in the use rate of analgesic drugs between the two treatment groups （,P,>,0.05）. ④On the 14th day after operation， the total effective rates of analgesia in the control group， treatment group A and treatment group B were 90.6%， 93.8% and 96.9% respectively. The analgesic efficacy of the treatment group A and treatment group B was better than that of the control group （,P,<,0.05）， but there was no statistical difference in analgesic efficacy between the two treatment groups （,P,>,0.05）.,Conclusion,2,Acupoint catgut embedding has significant effect in the prevention and treatment of postoperative pain of mixed hemorrhoids， which can reduce the postoperative complications， but there is no significant difference in the analgesic effect between single acupoint and multiple acupoint catgut embedding.