Objective： To observe the clinical effect of Tiaozhong Baoyuan Decoction in the treatment of delayed healing of long bone fracture after operation.,Methods,2,A total of 60 patients with delayed healing of long bone fracture after operation were included and randomly divided into the treatment group and control group， 30 cases in each group. The patients in the control group were treated with Alfacalcidol Soft Capsule orally and the patients in the treatment group were treated with Tiaozhong Baoyuan Decoction orally. The treatment course of both groups was 6 months. Before treatment， three months and six months after treatment， the fracture connection of the patients in the two groups was evaluated by fracture healing imaging score （RUST score）. Three months and six months after treatment， the clinical effects of the two groups were evaluated and compared. Before treatment and 6 months after treatment， the health status of the patients in the two groups was evaluated by the MOS item short from health survey （SF-36） scale.,Results,2,①Three months and six months after treatment， the RUST scores of the two groups were increased compared with those before treatment （,P,<,0.05）， and the score of the treatment group was higher than those of the control group （,P,<,0.05）. ②Three months and six months after treatment， the total clinical effective rates of the treatment group were 73.33% and 86.67% respectively， the total clinical effective rates of the control group were 40.00% and 53.33% respectively， and the clinical efficacy of the treatment group was better than that of the control group （,P,<,0.05）. ③Six months after treatment， the scores of physical function， role physical， social function， bodily pain and general health dimension score in the treatment group were significantly increased compared with those before treatment （,P,<,0.05）， the scores of physical function， role physical and bodily pain dimension score in the control group were also significantly increased compared with those before treatment （,P,<,0.05）， and the scores of physical function， role physical， social function， bodily pain and general health dimension score in the treatment group were significantly higher than those in the control group （,P,<,0.05）.,Conclusion,2,Tiaozhong Baoyuan Decoction can promote the callus growth and fracture healing， and effectively improve the health status of patients with delayed healing of long bone fracture after operation.