Objective： To observe the clinical effects of Penyan Formula combined with acupuncture on sequelae of pelvic inflammatory disease （SPID） with qi stagnation and blood stasis type.,Methods,2,A total of 108 SPID patients with qi stagnation and blood stasis type were included and randomly divided into the guideline group， traditional Chinese medicine group and acupuncture combined with traditional Chinese medicine group， 36 cases in each group. The patients in the guideline group were orally treated with Gexia Zhuyu Decoction， the patients in traditional Chinese medicine group were orally treated with Penyan Formula， and the patients in the acupuncture combined with traditional Chinese medicine group were treated with acupuncture based on the treatment of traditional Chinese medicine group. The treatment course was three menstrual cycles. The clinical effects of the three groups were evaluated. Before and after treatment， the subjective pain of the patients was evaluated by visual analogue scale （VAS）， and the levels of interleukin （IL）-10 and tumor necrosis factor-α （TNF-α） were detected.,Results,2,①After treatment， the clinical total effective rates of the guideline group， traditional Chinese medicine group and acupuncture combined with traditional Chinese medicine group were 61.11%， 72.22% and 86.11% respectively， with a statistical difference among the three groups （,P,<,0.05）. The effect of the acupuncture combined with traditional Chinese medicine group was better than that of traditional Chinese medicine group and the guideline group （,P,<,0.05）， and the effect of traditional Chinese medicine group was better than that of the guideline group （,P,<,0.05）. ②After treatment， the VAS scores of the three groups were significantly decreased （,P,<,0.05）， and the score of the acupuncture combined with traditional Chinese medicine group was lower than that of traditional Chinese medicine group and the guideline group （,P,<,0.05）， the score of traditional Chinese medicine group was lower than that of the guideline group （,P,<,0.05）. ③ After treatment， the levels of the serum TNF-α in the three groups were decreased and the levels of IL-10 were increased （,P,<,0.05）， and the level of IL-10 in the acupuncture combined with traditional Chinese medicine group was higher than that in the guideline group and traditional Chinese medicine group （,P,<,0.05）， the level of IL-10 in traditional Chinese medicine group was higher than that in the guideline group （,P,<,0.05）， the level of TNF-α in the acupuncture combined with traditional Chinese medicine group was lower than that in the guideline group and traditional Chinese medicine group （,P,<,0.05）.,Conclusion,2,Penyan Formula combined with acupuncture can effectively improve the pain symptom and regulate the levels of the related inflammatory indexes in the treatment of SPID with qi stagnation and blood stasis type， which is worth popularizing in clinic.