Objective： To prepare Huayu Capsule and establish a high performance liquid chromatography （HPLC） method for simultaneously determining five main components and providing basis for quality control of Huayu Capsule.,Methods,2,A proper number of medicinal materials were taken. The volatile oil was extracted by steam distillation， and then was prepared into a β-cyclodextrin inclusion complex by saturated aqueous solution method. The inclusion complex was mixed with concentrated extract and excipients to prepare granules， and then the capsules were obtained. The appearance， particle size， moisture， fluidity and solubility of the granules were detected， and the water content and disintegration time of the capsules were determined. The HPLC method was established for the content determination of naringin， hesperidin， neohesperidin， hydroxysafflower yellow A and amygdalin in Huayu Capsule， and the methodological investigation was performed.,Results,2,For the prepared Huayu Capsule， the yield of inclusion complex was 64.9% and the inclusion rate of volatile oil was 55.2%. All quality tests on granules and capsules were in accordance with the provisions of the pharmacopoeia. For the established HPLC method， the linear relationship， precision， repeatability， stability and recovery met the requirements. The average contents of naringin， hesperidin， neohesperidin， hydroxysafflower yellow A and amygdalin in six samples of Huayu Capsule were 7.56， 1.63， 4.84， 0.61 and 1.13 mg/g respectively.,Conclusion,2,The preparation process is simple and feasible. The established content determination method is simple and convenient， with good repeatability and stability and high precision， which can provide reference for the quality control of Huayu Capsule.